The building commissioned by Pope Alexander VII Chigi, formerly known as the Ospedaletto, represents the 17th-century expansion of Santo Spirito. It was constructed perpendicular to the 15th-century hospital, the Corsie Sistine, and faces the right bank of the Tiber. The Sala Alessandrina is accessed via a staircase in front of the large recessed portal. It is a spacious, rectangular hall, with a ceiling that still preserves its original wooden coffered structure. At the far end of the room, a monumental staircase adorned with plaster busts of renowned physicians rises symmetrically in a double flight, providing access to the upper floor. The Sala Alessandrina serves as an exhibition space for numerous graphic works by Antonio Serantoni from the 19th century, hand-colored anatomical plates, and several panel paintings that once belonged to the renowned physician Guglielmo Riva.



